| TAYLOR, Lucy ACTIVE | Secretary | 19 Dec 2024 | | | | Spirella Building, Multiple Sclerosis Trust, Spirella Building, Letchworth Garden City, Hertfordshire, SG6 4ET, United Kingdom |
| CLACY, Benjamin Toby ACTIVE | Director | 01 Nov 2011 | | England | April 1975 | 8, Carrick Gardens, Woodley, Reading, RG9 3JD, England |
| SINGLETON, Christine ACTIVE | Director | 04 Nov 2024 | | England | February 1956 | Spirella Building, Bridge Road, Letchworth, Hertfordshire, SG6 4ET, United Kingdom |
| SORRELL, Caitlin, Dr ACTIVE | Director | 05 Jan 2026 | | England | May 1974 | Spirella Building, Bridge Road, Letchworth, Hertfordshire, SG6 4ET, United Kingdom |
| ARR WOODWARD, Susan Margaret RESIGNED | Secretary | 23 Dec 1994 | 31 Mar 1997 | | | South Winds The Common, Potten End, Berkhamsted, Hertfordshire, HP4 2QF |
| CARPENTER, George Frederick RESIGNED | Secretary | 19 Nov 1997 | 01 Jul 2004 | | | Les Cory,, 20 Le Clos Du Verdun 83630, Aups, France |
| CLACY, Benjamin Toby RESIGNED | Secretary | 20 Apr 2012 | 19 Dec 2024 | | | 8, Carrick Gardens, Woodley, Reading, RG5 3JD, England |
| TACEY, William Arthur RESIGNED | Secretary | 03 Jun 2003 | 20 Apr 2012 | | | 9 Southfield Road, Westbury On Trym, Bristol, Avon, BS9 3BG |
| ARR, David Michael RESIGNED | Director | 23 Dec 1994 | 24 Aug 2004 | | June 1950 | 3 Birchalls, Stansted, Essex, CM24 8LQ |
| BUSCOMBE, Peta Jane, Baroness RESIGNED | Director | 23 Dec 1994 | 29 May 1996 | England | March 1954 | The Ferry House Ferry Lane, Goring On Thames, Reading, Berkshire, RG8 9DX |
| CARPENTER, George Frederick RESIGNED | Director | 23 Dec 1994 | 01 Sep 2015 | France | January 1939 | Les Cory,, 20 Le Clos Du Verdun 83630, Aups, France |
| DENNY, Charlotte Amanda RESIGNED | Director | 23 Dec 1994 | 29 May 1996 | | May 1958 | Old Farm House Silver Lane, Padworth Common, Reading, Berkshire, RG7 4QR |
| GORE, Robert Nicholas RESIGNED | Director | 22 Apr 2017 | 14 Feb 2020 | England | January 1968 | The Vassall Centre, Gill Avenue, Fishponds, Bristol, BS16 2QQ |
| GORE, Ropafadzo Pearl RESIGNED | Director | 26 Jul 2023 | 22 Nov 2023 | England | August 1994 | The Vassall Centre, Gill Avenue, Fishponds, Bristol, BS16 2QQ |
| HEARN, Michael RESIGNED | Director | 23 Dec 1994 | 23 Oct 1995 | | July 1928 | Somercombe House, 10 Battledown Drive, Cheltenham, Gloucestershire, GL52 6RX |
| JOINER, Sarah Louise, The Honorable RESIGNED | Director | 04 Nov 2024 | 11 Dec 2025 | England | March 1960 | Spirella Building, Bridge Road, Letchworth, Hertfordshire, SG6 4ET, United Kingdom |
| JONES, Rosemary Jennifer Suzette, Dr RESIGNED | Director | 03 Nov 2010 | 09 Dec 2022 | England | August 1942 | Trym Lodge, 1 Henbury Road, Westbury On Trym, Bristol, BS9 3HQ, England |
| MCCARTHY, Shaun Robert RESIGNED | Director | 20 Feb 2006 | 30 Apr 2008 | | March 1960 | 187 Ilchester Crescent, Bedminster Down, Bristol, Avon, BS13 7HR |
| PAGINGTON, Brian RESIGNED | Director | 25 Mar 2019 | 04 Nov 2024 | England | October 1957 | The Vassall Centre, Gill Avenue, Fishponds, Bristol, BS16 2QQ |
| PAGINGTON, Olga RESIGNED | Director | 25 Mar 2019 | 04 Nov 2024 | England | September 1950 | The Vassall Centre, Gill Avenue, Fishponds, Bristol, BS16 2QQ |
| ROBB, Laurence Eliane RESIGNED | Director | 14 Jul 2008 | 10 Sep 2023 | United Kingdom | November 1955 | 26, Rodney Road, Saltford, Bristol, Avon, BS31 3HP |
| SMALLWOOD, Janet Christina RESIGNED | Director | 23 Dec 1994 | 19 Oct 1995 | England | May 1958 | 17 Charles Street, Berkhamsted, Hertfordshire, HP4 3DG |
| SOOD, Neil RESIGNED | Director | 19 May 2023 | 04 Nov 2024 | England | November 1978 | The Vassall Centre, Gill Avenue, Fishponds, Bristol, BS16 2QQ |
| STEWART, Anna Maria RESIGNED | Director | 06 Jun 1995 | 29 May 1996 | | February 1961 | 23 Warwick Square, Pimlico, London, SW1V 2AB |
| TACEY, William Arthur RESIGNED | Director | 03 Jun 2003 | 14 Feb 2011 | United Kingdom | October 1939 | 9 Southfield Road, Westbury On Trym, Bristol, Avon, BS9 3BG |
| TARR, Steven John RESIGNED | Director | 03 Jun 2003 | 30 Apr 2008 | England | November 1975 | 14, Blaisedell View, Bristol, Avon, BS10 7XB |
| TARR, Stuart Mervyn RESIGNED | Director | 01 Nov 2011 | 03 Sep 2012 | England | February 1947 | 4, Moor Gate, Portishead, Bristol, BS20 7FL, England |
| WILLIAMS, Andrew Stephen RESIGNED | Director | 14 Nov 2008 | 13 Sep 2014 | England | July 1956 | 102, Lisburn Road, Knowle, Bristol, BS4 1NG |
| ZAUM, Phillippa Cotton RESIGNED | Director | 09 Jun 2023 | 03 Oct 2023 | England | October 1978 | The Vassall Centre, Gill Avenue, Fishponds, Bristol, BS16 2QQ |